李阳,副研究员、硕士生导师。2015年毕业于厦门大学获得博士学位。主要从事纳米药物在肿瘤精准治疗方面的基础研究与转化应用。曾主持国家自然科学基金青年项目、国家自然科学基金面上项目、厦门市青年创新基金项目、中国博士后科学基金特别资助和面上项目以及厦门市青年创新基金项目等。近年来在ACS Nano和J. Control. Release等国际顶级期刊合作发表10余篇SCI论文。
研究方向:
1. 研发稀土金属配位驱动的抗肿瘤药物自组装体系
2. 开发肿瘤微环境响应的靶向纳米药物输送系统
E-mail: li.yang@fjirsm.ac.cn
近期代表性成果:
1. Li, Yang#, Lin, Jin-Yan#, Wang, Pei-Yuan, Luo, Qiang, Lin, Hui-Rong, Zhang, Yun, Hou, Zhen-Qing, Liu, Jing-Feng *, Liu, Xiao-Long*. Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy, ACS Nano, 2019, 13:12912-12928.
2. Li, Yang#, Lin, Jin-Yan#, Wang, Pei-Yuan, Luo, Qiang, Zhu, Fu-Kai, Zhang, Yun, Hou, Zhen-Qing, Liu, Xiao-Long*, Liu, Jing-Feng*. Tumor Microenvironment Cascade-Responsive Nanodrug with Self-Targeting Activation and ROS Regeneration for Synergistic Oxidation-Chemotherapy, Nano-Micro Letter, 2020, 12:182-199.
3. Li, Yang#, Lin, Jin-Yan#, Cai, Zhi-Xiong, Wang, Pei-Yuan, Luo, Qiang, Zhang, Yun, Hou, Zhen-Qing*, Liu, Jing-Feng*, Liu, Xiao-Long*. Tumor Microenvironment-Activated Self-Recognizing Nanodrug through Directly Tailored Assembly of Small-Molecules for Targeted Synergistic Chemotherapy, Journal of Controlled Release, 2020, 321:222-235.
4. Li, Yang#, Liu, Gui-Hua#, Ma, Jin-Yuan, Lin, Jin-Yan, Lin, Hui-Rong, Su, Guang-Hao, Chen, Deng-Yue, Ye, She-Fang, Chen, Xiao-Yuan, Zhu, Xuan*, Hou, Zhen-Qing*. Chemotherapeutic Drug-Photothermal Agent Co-Self-Assembling Nanoparticles for Near-Infrared Fluorescence and Photoacoustic Dual-Modal Imaging-Guided Chemo-Photothermal Synergistic Therapy, Journal of Controlled Release, 2017, 258:95-107